Poxviruses capture host genes by LINE-1 retrotransposition

Horizontal gene transfer (HGT) provides a major source of genetic variation. Many viruses, including poxviruses, encode genes with crucial functions directly gained by gene transfer from hosts. The mechanism of transfer to poxvirus genomes is unknown. Using genome analysis and experimental screens o...

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Bibliographic Details
Main Authors: Sarah M Fixsen, Kelsey R Cone, Stephen A Goldstein, Thomas A Sasani, Aaron R Quinlan, Stefan Rothenburg, Nels C Elde
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/63332