Mesenchymal stem cells under epigenetic control – the role of epigenetic machinery in fate decision and functional properties

Abstract Mesenchymal stem cells (mesenchymal stromal cells, MSC) are multipotent stem cells that can differentiate into cells of at least three mesodermal lineages, namely adipocytes, osteoblasts, and chondrocytes, and have potent immunomodulatory properties. Epigenetic modifications are critical re...

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Bibliographic Details
Main Authors: Alicja Walewska, Adrian Janucik, Marlena Tynecka, Marcin Moniuszko, Andrzej Eljaszewicz
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06239-4