Bayesian meta-analysis of inter-phenotypic differences in human serum paraoxonase-1 activity for chemical risk assessment

Human variability in paraoxonase-1 (PON1) activities is driven by genetic polymorphisms that affect the internal dose of active oxons of organophosphorus (OP) insecticides. Here, an extensive literature search has been performed to collect human genotypic frequencies (i.e. L55M, Q192R, and C-108T) i...

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Bibliographic Details
Main Authors: K. Darney, E.E.J. Kasteel, F.M. Buratti, L. Turco, S. Vichi, C. Béchaux, A.C. Roudot, N.I. Kramer, E. Testai, J.L.C.M. Dorne, E. Di Consiglio, L.S. Lautz
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Environment International
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412019344654