Bayesian meta-analysis of inter-phenotypic differences in human serum paraoxonase-1 activity for chemical risk assessment
Human variability in paraoxonase-1 (PON1) activities is driven by genetic polymorphisms that affect the internal dose of active oxons of organophosphorus (OP) insecticides. Here, an extensive literature search has been performed to collect human genotypic frequencies (i.e. L55M, Q192R, and C-108T) i...
Main Authors: | K. Darney, E.E.J. Kasteel, F.M. Buratti, L. Turco, S. Vichi, C. Béchaux, A.C. Roudot, N.I. Kramer, E. Testai, J.L.C.M. Dorne, E. Di Consiglio, L.S. Lautz |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-05-01
|
Series: | Environment International |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0160412019344654 |
Similar Items
-
Human variability in polymorphic CYP2D6 metabolism: Implications for the risk assessment of chemicals in food and emerging designer drugs
by: K. Darney, et al.
Published: (2021-11-01) -
An open source physiologically based kinetic model for the chicken (Gallus gallus domesticus): Calibration and validation for the prediction residues in tissues and eggs
by: L.S. Lautz, et al.
Published: (2020-03-01) -
Congeners-Specific Intestinal Absorption Of Microcystins In An In Vitro 3D Human Intestinal Epithelium: The Role Of Influx/Efflux Transporters
by: Laura Turco, et al.
Published: (2022-08-01) -
Paraoxonase 1 Phenotype and Paraoxonase Activity in Asthmatic Patients
by: Nurhan Sarioglu, et al.
Published: (2015-02-01) -
GENETIC POLYMORPHISMS AND ACTIVITIES OF PARAOXONASE IN THE PANAMANIAN POPULATION
by: Ana E. Tejada E, et al.
Published: (2010-03-01)