Nucleotide excision repair is not induced in human embryonic lung fibroblasts treated with environmental pollutants.

The cellular response to genotoxic treatment depends on the cell line used. Although tumor cell lines are widely used for genotoxicity tests, the interpretation of the results may be potentially hampered by changes in cellular processes caused by malignant transformation. In our study we used normal...

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Bibliographic Details
Main Authors: Pavel Rossner, Andrea Mrhalkova, Katerina Uhlirova, Milada Spatova, Andrea Rossnerova, Helena Libalova, Jana Schmuczerova, Alena Milcova, Jan Topinka, Radim J Sram
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3716811?pdf=render