SAM domain-based protein oligomerization observed by live-cell fluorescence fluctuation spectroscopy.

Sterile-alpha-motif (SAM) domains are common protein interaction motifs observed in organisms as diverse as yeast and human. They play a role in protein homo- and hetero-interactions in processes ranging from signal transduction to RNA binding. In addition, mutations in SAM domain and SAM-mediated o...

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Bibliographic Details
Main Authors: Brian D Slaughter, Joseph M Huff, Winfried Wiegraebe, Joel W Schwartz, Rong Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2291563?pdf=render