Computer-assisted quantification of tumor-associated collagen signatures to improve the prognosis prediction of breast cancer

Abstract Background Collagen fibers play an important role in tumor initiation, progression, and invasion. Our previous research has already shown that large-scale tumor-associated collagen signatures (TACS) are powerful prognostic biomarkers independent of clinicopathological factors in invasive br...

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Bibliographic Details
Main Authors: Gangqin Xi, Lida Qiu, Shuoyu Xu, Wenhui Guo, Fangmeng Fu, Deyong Kang, Liqin Zheng, Jiajia He, Qingyuan Zhang, Lianhuang Li, Chuan Wang, Jianxin Chen
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12916-021-02146-7