Human MxA is a potent interspecies barrier for the novel bat-derived influenza A-like virus H18N11
ABSTRACTThe human innate immune factor MxA represents an effective interspecies barrier for zoonotic influenza A viruses (IAVs) of animal origin. Accordingly, human but not avian IAVs efficiently escape the antiviral activity of MxA due to adaptive mutations in their viral nucleoprotein. Partial MxA...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2019-01-01
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Series: | Emerging Microbes and Infections |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2019.1599301 |