Human MxA is a potent interspecies barrier for the novel bat-derived influenza A-like virus H18N11

ABSTRACTThe human innate immune factor MxA represents an effective interspecies barrier for zoonotic influenza A viruses (IAVs) of animal origin. Accordingly, human but not avian IAVs efficiently escape the antiviral activity of MxA due to adaptive mutations in their viral nucleoprotein. Partial MxA...

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Bibliographic Details
Main Authors: Kevin Ciminski, Johanna Pulvermüller, Julia Adam, Martin Schwemmle
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2019.1599301