The Effects of Safinamide Adjunct Therapy on Depression and Apathy in Patients With Parkinson's Disease: Post-hoc Analysis of a Japanese Phase 2/3 Study

The Effects of Safinamide Adjunct Therapy on Depression and Apathy in Patients With Parkinson's Disease: Post-hoc Analysis of a Japanese Phase 2/3 Study

Background and PurposeNeuropsychiatric symptoms in Parkinson's disease (PD) have been shown to significantly affect quality of life (QOL). We investigated the impact of safinamide on depression and apathy when administered as an adjunct to levodopa in Japanese patients with PD.MethodsThis was a...

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Bibliographic Details
Main Authors: Nobutaka Hattori, Yuki Kogo, Michinori Koebis, Takayuki Ishida, Ippei Suzuki, Yoshio Tsuboi, Masahiro Nomoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Neurology
Subjects:
clinical trial
MAO-B inhibitor
depression
apathy
Parkinson's disease
post-hoc analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.752632/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2021.752632/full

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