Raptor couples mTORC1 and ERK1/2 inhibition by cardamonin with oxidative stress induction in ovarian cancer cells

Background A balance on nutrient supply and redox homeostasis is required for cell survival, and increased antioxidant capacity of cancer cells may lead to chemotherapy failure. Objective To investigate the mechanism of anti-proliferation of cardamonin by inducing oxidative stress in ovarian cancer...

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Bibliographic Details
Main Authors: Yanting Zhu, Shifeng Wang, Peiguang Niu, Huajiao Chen, Jintuo Zhou, Li Jiang, Danyun Li, Daohua Shi
Format: Article
Language:English
Published: PeerJ Inc. 2023-06-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/15498.pdf