5-aminosalicylic acid suppresses osteoarthritis through the OSCAR-PPARγ axis
Abstract Osteoarthritis (OA) is a progressive and irreversible degenerative joint disease that is characterized by cartilage destruction, osteophyte formation, subchondral bone remodeling, and synovitis. Despite affecting millions of patients, effective and safe disease-modifying osteoarthritis drug...
Autori principali: | , , , , , , , , , , , , , , |
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Natura: | Articolo |
Lingua: | English |
Pubblicazione: |
Nature Portfolio
2024-02-01
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Serie: | Nature Communications |
Accesso online: | https://doi.org/10.1038/s41467-024-45174-6 |