KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas

KLF3 and PAX6 are candidate driver genes in late-stage, MSI-hypermutated endometrioid endometrial carcinomas

Endometrioid endometrial carcinomas (EECs) are the most common histological subtype of uterine cancer. Late-stage disease is an adverse prognosticator for EEC. The purpose of this study was to analyze EEC exome mutation data to identify late-stage-specific statistically significantly mutated genes (...

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Bibliographic Details
Main Authors: Meghan L. Rudd, Nancy F. Hansen, Xiaolu Zhang, Mary Ellen Urick, Suiyuan Zhang, Maria J. Merino, National Institutes of Health Intramural Sequencing Center Comparative Sequencing Program, James C. Mullikin, Lawrence C. Brody, Daphne W. Bell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791453/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791453/?tool=EBI

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