Fulvestrant increases the susceptibility of enzalutamide-resistant prostate cancer cells to NK-mediated lysis

Background Enzalutamide, a next-generation antiandrogen agent, is approved for the treatment of metastatic castration-resistant prostate cancer (CRPC). While enzalutamide has been shown to improve time to progression and extend overall survival in men with CRPC, the majority of patients ultimately d...

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Bibliographic Details
Main Authors: Jeffrey Schlom, Claudia Palena, Kristen Fousek, Duane H Hamilton, Lucas A Horn, Haiyan Qin, Madeline Dahut, Shantel Angstadt
Format: Article
Language:English
Published: BMJ Publishing Group 2023-09-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/9/e007386.full