Stimulation of Suicidal Erythrocyte Death by Ceritinib-Treatment of Human Erythrocytes

Stimulation of Suicidal Erythrocyte Death by Ceritinib-Treatment of Human Erythrocytes

Background/Aims: The anaplastic lymphoma kinase (ALK) inhibitor ceritinib is utilized for the treatment of ALK positive non-small cell lung carcinoma. Side effects of the drug include decrease of blood hemoglobin concentration. Possible causes of anemia include stimulation of suicidal erythrocyte de...

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Bibliographic Details
Main Authors: Abdulla Al Mamun Bhuyan, Elena Signoretto, Rosi Bissinger, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Phosphatidylserine
Cell volume
Eryptosis
Ionomycin
Calcium
Online Access:http://www.karger.com/Article/FullText/453167

Internet

http://www.karger.com/Article/FullText/453167

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