Role of Lipocalin-2 in Amyloid-Beta Oligomer-Induced Mouse Model of Alzheimer’s Disease

Role of Lipocalin-2 in Amyloid-Beta Oligomer-Induced Mouse Model of Alzheimer’s Disease

Lipocalin-2 (LCN2) is an inflammatory protein with diverse functions in the brain. Although many studies have investigated the mechanism of LCN2 in brain injuries, the effect of LCN2 on amyloid-toxicity-related memory deficits in a mouse model of Alzheimer’s disease (AD) has been less studied. We in...

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Bibliographic Details
Main Authors: Heeyoung Kang, Hyun Joo Shin, Hyeong Seok An, Zhen Jin, Jong Youl Lee, Jaewoong Lee, Kyung Eun Kim, Eun Ae Jeong, Kyu Yeong Choi, Catriona McLean, Kun Ho Lee, Soo Kyoung Kim, Hae Ryong Lee, Gu Seob Roh
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Antioxidants
Subjects:
lipocalin-2
amyloid-beta
neuroinflammation
iron accumulation
oxidative stress
blood–brain barrier leakage
Online Access:https://www.mdpi.com/2076-3921/10/11/1657

Internet

https://www.mdpi.com/2076-3921/10/11/1657

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