Secondary-structure switch regulates the substrate binding of a YopJ family acetyltransferase
The Yersinia outer protein J (YopJ) family of effectors, which are present in many plant and animal pathogens are non-canonical acetyltransferases that are activated by the eukaryote-specific cofactor inositol hexaphosphate (InsP6). Here, the authors combine X-ray crystallography, biochemical and fu...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-10-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-26183-1 |