LRRK2 and Lipid Pathways: Implications for Parkinson’s Disease

Genetic alterations in the <i>LRRK2</i> gene, encoding leucine-rich repeat kinase 2, are a common risk factor for Parkinson’s disease. How LRRK2 alterations lead to cell pathology is an area of ongoing investigation, however, multiple lines of evidence suggest a role for LRRK2 in lipid p...

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Bibliographic Details
Main Authors: Jasmin Galper, Woojin S. Kim, Nicolas Dzamko
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/11/1597