Antimicrobial Activity of Some Novel Armed Thiophene Derivatives and Petra/Osiris/Molinspiration (POM) Analyses

Tetrasubstituted 2-acetylthiophene derivative 5 was synthesized and then condensed with various nitrogen nucleophiles such as 5-amino-1,2,4-triazole, 2-aminobenzimidazole, aniline or p-chloroaniline to afford the corresponding iminothiophene derivatives 6–8a,b. Condensation of thiophene 5 with malon...

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Bibliographic Details
Main Authors: Yahia Nasser Mabkhot, Fatima Alatibi, Nahed Nasser E. El-Sayed, Salim Al-Showiman, Nabila Abdelshafy Kheder, Abdul Wadood, Abdur Rauf, Saud Bawazeer, Taibi Ben Hadda
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/2/222