Old drugs, new tricks: leveraging known compounds to disrupt coronavirus-induced cytokine storm
Abstract A major complication in COVID-19 infection consists in the onset of acute respiratory distress fueled by a dysregulation of the host immune network that leads to a run-away cytokine storm. Here, we present an in silico approach that captures the host immune system’s complex regulatory dynam...
Main Authors: | Spencer Richman, Cole Lyman, Anastasia Nesterova, Anton Yuryev, Matthew Morris, Hongbao Cao, Chris Cheadle, Gary Skuse, Gordon Broderick |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-10-01
|
Series: | npj Systems Biology and Applications |
Online Access: | https://doi.org/10.1038/s41540-022-00250-9 |
Similar Items
-
Cytokine Storm
by: Gaestel, Matthias, et al.
Published: (2021) -
Cytokine Storm
by: Gaestel, Matthias, et al.
Published: (2021) -
Into the eye of the cytokine storm.
by: Tisoncik, JR, et al.
Published: (2012) -
Into the eye of the cytokine storm
by: Tisoncik, J, et al.
Published: (2012) -
Role of cytokine storm in coronavirus infections: culprit or accomplice?
by: Rongpeng Xu, et al.
Published: (2022-03-01)