Syphilis and the host: multi-omic analysis of host cellular responses to Treponema pallidum provides novel insight into syphilis pathogenesis

Syphilis and the host: multi-omic analysis of host cellular responses to Treponema pallidum provides novel insight into syphilis pathogenesis

IntroductionSyphilis is a chronic, multi-stage infection caused by the extracellular bacterium Treponema pallidum ssp. pallidum. Treponema pallidum widely disseminates through the vasculature, crosses endothelial, blood–brain and placental barriers, and establishes systemic infection. Although the c...

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Bibliographic Details
Main Authors: Sean Waugh, Akash Ranasinghe, Alloysius Gomez, Simon Houston, Karen V. Lithgow, Azad Eshghi, Jenna Fleetwood, Kate M. E. Conway, Lisa A. Reynolds, Caroline E. Cameron
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Microbiology
Subjects:
syphilis
Treponema pallidum
proteomics
dissemination
disease symptoms
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1254342/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1254342/full

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