Selective preservation of bone marrow mature recirculating but not marginal zone B cells in murine models of chronic inflammation.

Selective preservation of bone marrow mature recirculating but not marginal zone B cells in murine models of chronic inflammation.

Inflammation promotes granulopoiesis over B lymphopoiesis in the bone marrow (BM). We studied B cell homeostasis in two murine models of T cell mediated chronic inflammation, namely calreticulin-deficient fetal liver chimeras (FLC), which develop severe blepharitis and alopecia due to T cell hyper r...

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Bibliographic Details
Main Authors: Elisabetta Traggiai, Anna Casati, Michela Frascoli, Simona Porcellini, Maurilio Ponzoni, Francesca Sanvito, Lin Leng, Richard Bucala, Lorenzo Moretta, Fabio Grassi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2889832?pdf=render

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http://europepmc.org/articles/PMC2889832?pdf=render

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