Physio-pathological effects of N6-methyladenosine and its therapeutic implications in leukemia

Abstract N6-methyladenosine (m6A), the most prevalent epigenetic modification of RNA in mammals, has become a hot topic throughout recent years. m6A is involved with every links of the RNA fate, including RNA splicing, nuclear export, translation and stability. Due to the reversible and dynamic regu...

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Bibliographic Details
Main Authors: Wei-Wei Liu, Hao Wang, Xiao-Yu Zhu
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Biomarker Research
Subjects:
Online Access:https://doi.org/10.1186/s40364-022-00410-3