Loss of OVOL2 in Triple‐Negative Breast Cancer Promotes Fatty Acid Oxidation Fueling Stemness Characteristics

Loss of OVOL2 in Triple‐Negative Breast Cancer Promotes Fatty Acid Oxidation Fueling Stemness Characteristics

Abstract Triple‐negative breast cancer (TNBC), the most aggressive subtype of breast cancer, has a poor prognosis and lacks effective treatment strategies. Here, the study discovered that TNBC shows a decreased expression of epithelial transcription factor ovo‐like 2 (OVOL2). The loss of OVOL2 promo...

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Bibliographic Details
Main Authors: Ruipeng Lu, Jingjing Hong, Tong Fu, Yu Zhu, Ruiqi Tong, Di Ai, Shuai Wang, Qingsong Huang, Ceshi Chen, Zhiming Zhang, Rui Zhang, Huiling Guo, Boan Li
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:Advanced Science
Subjects:
FAO
JAK/STAT3
Ovol2
stemness characteristics
TNBC
Online Access:https://doi.org/10.1002/advs.202308945

Internet

https://doi.org/10.1002/advs.202308945

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