The Hippo Pathway Effectors YAP/TAZ Are Essential for Mineralized Tissue Homeostasis in the Alveolar Bone/Periodontal Complex

The Hippo Pathway Effectors YAP/TAZ Are Essential for Mineralized Tissue Homeostasis in the Alveolar Bone/Periodontal Complex

YAP and TAZ are essential transcriptional co-activators and downstream effectors of the Hippo pathway, regulating cell proliferation, organ growth, and tissue homeostasis. To ask how the Hippo pathway affects mineralized tissue homeostasis in a tissue that is highly reliant on a tight homeostatic co...

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Bibliographic Details
Main Authors: Mirali Pandya, Gokul Gopinathan, Connie Tillberg, Jun Wang, Xianghong Luan, Thomas G. H. Diekwisch
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Journal of Developmental Biology
Subjects:
Hippo pathway
YAP1
agrin
unopposed molar
Online Access:https://www.mdpi.com/2221-3759/10/1/14

Internet

https://www.mdpi.com/2221-3759/10/1/14

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