Biosynthetic Microcin J25 Exerts Strong Antibacterial, Anti-Inflammatory Activities, Low Cytotoxicity Without Increasing Drug-Resistance to Bacteria Target

Biosynthetic Microcin J25 Exerts Strong Antibacterial, Anti-Inflammatory Activities, Low Cytotoxicity Without Increasing Drug-Resistance to Bacteria Target

Multidrug resistant (MDR) bacterial infection has emerged, raising concerns about untreatable infections, and posing the highest health risks. Antimicrobial peptides (AMPs) are thought to be the best remedy for this problem. Here, we showed biosynthetic microcin J25 (MccJ25) exhibited excellent bact...

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Bibliographic Details
Main Authors: Haitao Yu, Lijun Shang, Guangxin Yang, Ziqi Dai, Xiangfang Zeng, Shiyan Qiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
antimicrobial peptide microcin J25
multidrug resistance
antimicrobial activity
mode of action
cytotoxicity
bacterial infection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.811378/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.811378/full

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