Canadian Consensus Recommendations on the Management of KRAS G12C-Mutated NSCLC

Canadian Consensus Recommendations on the Management of KRAS G12C-Mutated NSCLC

Activating mutations in <i>Kirsten rat sarcoma viral oncogene homologue (KRAS)</i>, in particular, a point mutation leading to a glycine-to-cysteine substitution at codon 12 (G12C), are among the most frequent genomic alterations in non-small cell lung cancer (NSCLC). Several agents targ...

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Bibliographic Details
Main Authors: Parneet K. Cheema, Shantanu O. Banerji, Normand Blais, Quincy S.-C. Chu, Rosalyn A. Juergens, Natasha B. Leighl, Adrian Sacher, Brandon S. Sheffield, Stephanie Snow, Mark Vincent, Paul F. Wheatley-Price, Stephen Yip, Barbara L. Melosky
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Current Oncology
Subjects:
KRAS G12C
NSCLC
targeted therapy
immune checkpoint inhibitors
mutation testing
resistance
Online Access:https://www.mdpi.com/1718-7729/30/7/476

Internet

https://www.mdpi.com/1718-7729/30/7/476

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