Contrasting properties of gene-specific regulatory, coding, and copy number mutations in Saccharomyces cerevisiae: frequency, effects, and dominance.

Genetic variation within and between species can be shaped by population-level processes and mutation; however, the relative impact of "survival of the fittest" and "arrival of the fittest" on phenotypic evolution remains unclear. Assessing the influence of mutation on evolution...

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Bibliographic Details
Main Authors: Jonathan D Gruber, Kara Vogel, Gizem Kalay, Patricia J Wittkopp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3276545?pdf=render