<i>Rumex japonicus</i> Houtt. Protects Dopaminergic Neurons by Regulating Mitochondrial Function and Gut–Brain Axis in In Vitro and In Vivo Models of Parkinson’s Disease

<i>Rumex japonicus</i> Houtt. Protects Dopaminergic Neurons by Regulating Mitochondrial Function and Gut–Brain Axis in In Vitro and In Vivo Models of Parkinson’s Disease

Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide. <i>Rumex japonicus</i> Houtt. (RJ) has been used to treat gastrointestinal and inflammatory diseases in East Asia. However, it is unknown whether RJ can prevent PD. We investigated the neuroprotective...

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Bibliographic Details
Main Authors: Hee-Young Kim, Chang-Hwan Bae, Jayoung Kim, Yukyoung Lee, Hyongjun Jeon, Hyungwoo Kim, Seungtae Kim
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Antioxidants
Subjects:
<i>Rumex japonicus</i> Houtt.
Parkinson’s disease
neurodegeneration
neuroinflammation
tight junction
α-synuclein
Online Access:https://www.mdpi.com/2076-3921/11/1/141

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https://www.mdpi.com/2076-3921/11/1/141

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