NeuroAid™-II (MLC901) provides neuroprotection and enhances neuronal cell survival against kainic acid-induced excitotoxicity in vitro by activating the PI3K/AKT pathway

NeuroAid™-II (MLC901) provides neuroprotection and enhances neuronal cell survival against kainic acid-induced excitotoxicity in vitro by activating the PI3K/AKT pathway

Abstract In the twenty-first century, in vitro models of excitotoxic injury, leveraging advanced cellular and molecular technologies, offer a promising alternative to animal studies. These models provide a more precise understanding of injury mechanisms. Method: This study utilizes kainic acid (KA),...

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书目详细资料
Main Authors: Anam Anjum, Muhammad Dain Yazid, Muhammad Fauzi Daud, Jalilah Idris, Angela Min Hwei Ng, Amaramalar Selvi Naicker, Ohnmar Htwe Ismail, Ramesh Kumar Athi Kumar, Yogeswaran Lokanathan
格式: 文件
语言:English
出版: SpringerOpen 2025-03-01
丛编:Future Journal of Pharmaceutical Sciences
主题:
Chemical injury
Kainic acid
Excitotoxicity
In vitro model
MLC901
Neuroprotection
在线阅读:https://doi.org/10.1186/s43094-025-00782-x

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https://doi.org/10.1186/s43094-025-00782-x

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