An Interplay of S-Nitrosylation and Metal Ion Binding for Astrocytic S100B Protein.

Mammalian S100B protein plays multiple important roles in cellular brain processes. The protein is a clinically used marker for several pathologies including brain injury, neurodegeneration and cancer. High levels of S100B released by astrocytes in Down syndrome patients are responsible for reduced...

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Bibliographic Details
Main Authors: Małgorzata Bajor, Monika Zaręba-Kozioł, Liliya Zhukova, Krzysztof Goryca, Jarosław Poznański, Aleksandra Wysłouch-Cieszyńska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4861259?pdf=render