Targeting Wnt/β-Catenin Signaling Exacerbates Ferroptosis and Increases the Efficacy of Melanoma Immunotherapy via the Regulation of MITF

Targeting Wnt/β-Catenin Signaling Exacerbates Ferroptosis and Increases the Efficacy of Melanoma Immunotherapy via the Regulation of MITF

Melanoma is the most lethal form of skin cancer, resulting from the malignant transformation of epidermal melanocytes. Recent revolutionary progress in targeted therapy and immunotherapy has prominently improved the treatment outcome, but the survival of melanoma patients remains suboptimal. Ferropt...

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Bibliographic Details
Main Authors: Hao Wang, Hengxiang Zhang, Yuhan Chen, Huina Wang, Yangzi Tian, Xiuli Yi, Qiong Shi, Tao Zhao, Baolu Zhang, Tianwen Gao, Sen Guo, Chunying Li, Weinan Guo
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
Wnt/β-catenin
MITF
ferroptosis
melanoma
anti-PD-1 immunotherapy
Online Access:https://www.mdpi.com/2073-4409/11/22/3580

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https://www.mdpi.com/2073-4409/11/22/3580

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