Post-synaptic GABAA receptors potentiate transmission by recruiting CaV2 channels to their inputs
Summary: We describe a retrograde synaptic signal at the C. elegans GABAergic neuromuscular junction. At this synapse, GABA release is controlled by two voltage-activated calcium channels (UNC-2/CaV2 and EGL-19/CaV1), and muscle responses are mediated by a single GABA receptor (UNC-49/GABAA). Mutati...
Glavni autori: | , , , |
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Format: | Članak |
Jezik: | English |
Izdano: |
Elsevier
2023-10-01
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Serija: | Cell Reports |
Teme: | |
Online pristup: | http://www.sciencedirect.com/science/article/pii/S2211124723011737 |