Interactions between Nef and AIP1 proliferate multivesicular bodies and facilitate egress of HIV-1

<p>Abstract</p> <p>Background</p> <p>Nef is an accessory protein of primate lentiviruses, HIV-1, HIV-2 and SIV. Besides removing CD4 and MHC class I from the surface and activating cellular signaling cascades, Nef also binds GagPol during late stages of the viral replic...

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Bibliographic Details
Main Authors: Plemenitas Ana, Tanuri Amilcar, Aguiar Renato S, Lopes Adriana, Chen Nan, Costa Luciana J, Peterlin B Matija
Format: Article
Language:English
Published: BMC 2006-06-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/3/1/33