Inteins—mechanism of protein splicing, emerging regulatory roles, and applications in protein engineering

Protein splicing is a posttranslational process in which an intein segment excises itself from two flanking peptides, referred to as exteins. In the native context, protein splicing results in two separate protein products coupled to the activation of the intein-containing host protein. Inteins are...

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Bibliographic Details
Main Authors: David W. Wood, Marlene Belfort, Christopher W. Lennon
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1305848/full