Transplantation of gut microbiota from old mice into young healthy mice reduces lean mass but not bone mass

Transplantation of gut microbiota from old mice into young healthy mice reduces lean mass but not bone mass

ABSTRACTAging is associated with low bone and lean mass as well as alterations in the gut microbiota (GM). In this study, we determined whether the reduced bone mass and relative lean mass observed in old mice could be transferred to healthy young mice by GM transplantation (GMT). GM from old (21-mo...

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Bibliographic Details
Main Authors: Lina Lawenius, Carrie Cowardin, Louise Grahnemo, Julia M. Scheffler, Karin Horkeby, Cecilia Engdahl, Jianyao Wu, Liesbeth Vandenput, Antti Koskela, Juha Tuukkanen, Eivind Coward, Kristian Hveem, Arnulf Langhammer, Sanna Abrahamsson, Jeffrey I. Gordon, Klara Sjögren, Claes Ohlsson
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Gut microbiota
germ-free mice
gut microbiota transplantation
bone mass
osteoporosis
lean mass
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2236755

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https://www.tandfonline.com/doi/10.1080/19490976.2023.2236755

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