Expression analysis of tissue factor pathway inhibitors TFPI-1 and TFPI-2 in Paralichthys olivaceus and antibacterial and anticancer activity of derived peptides

Expression analysis of tissue factor pathway inhibitors TFPI-1 and TFPI-2 in Paralichthys olivaceus and antibacterial and anticancer activity of derived peptides

Abstract Tissue factor pathway inhibitors (TFPI), including TFPI-1 and TFPI-2, are Kunitz-type serine protease inhibitors that mainly inhibit the blood coagulation induced by tissue factors. Previous reports on teleost proved TFPI play important roles in innate immunity. In this study, two TFPI (PoT...

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Bibliographic Details
Main Authors: Guanghua Wang, Bing Xie, Yanli Su, Qinqin Gu, Dongfang Hao, Hongmei Liu, Changbiao Wang, Yonghua Hu, Min Zhang
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Veterinary Research
Subjects:
Paralichthys olivaceus
TFPI
C-terminal peptides
Antibacterial activity
Anticancer cell activity
Online Access:https://doi.org/10.1186/s13567-021-00908-y

Internet

https://doi.org/10.1186/s13567-021-00908-y

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