CDNF and MANF in the brain dopamine system and their potential as treatment for Parkinson’s disease

Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by gradual loss of midbrain dopamine neurons, leading to impaired motor function. Preclinical studies have indicated cerebral dopamine neurotrophic factor (CDNF) and mesencephalic astrocyte-derived neurotrophic factor...

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Bibliographic Details
Main Authors: Emmi Pakarinen, Päivi Lindholm
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1188697/full