Genetic Evidence for Roles of Yeast Mitotic Cyclins at Single-Stranded Gaps Created by DNA Replication

Genetic Evidence for Roles of Yeast Mitotic Cyclins at Single-Stranded Gaps Created by DNA Replication

Paused or stalled replication forks are major threats to genome integrity; unraveling the complex pathways that contribute to fork stability and restart is crucial. Experimentally, fork stalling is induced by growing the cells in presence of hydroxyurea (HU), which depletes the pool of deoxynucleoti...

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Bibliographic Details
Main Author: Laurence Signon
Format: Article
Language:English
Published: Oxford University Press 2018-02-01
Series:G3: Genes, Genomes, Genetics
Subjects:
mitotic cyclin
replication
hydroxyurea
stalled forks
SGS1 helicase
EXO1 nuclease
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.300537

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http://g3journal.org/lookup/doi/10.1534/g3.117.300537

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