Fractures in Osteogenesis Imperfecta: Pathogenesis, Treatment, Rehabilitation and Prevention

Fractures in patients with osteogenesis imperfecta (OI) are caused by a decreased strength of bone due to a decreased quality and quantity of bone matrix and architecture. Mutations in the collagen type 1 encoding genes cause the altered formation of collagen type I, one of the principal building bl...

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Bibliographic Details
Main Authors: Wouter Nijhuis, Marjolein Verhoef, Christiaan van Bergen, Harrie Weinans, Ralph Sakkers
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/9/2/268