Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs, and mRNAs in live bacterial cells

Dynamic interactions between the RNA chaperone Hfq, small regulatory RNAs, and mRNAs in live bacterial cells

RNA-binding proteins play myriad roles in regulating RNAs and RNA-mediated functions. In bacteria, the RNA chaperone Hfq is an important post-transcriptional gene regulator. Using live-cell super-resolution imaging, we can distinguish Hfq binding to different sizes of cellular RNAs. We demonstrate t...

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Bibliographic Details
Main Authors: Seongjin Park, Karine Prévost, Emily M Heideman, Marie-Claude Carrier, Muhammad S Azam, Matthew A Reyer, Wei Liu, Eric Massé, Jingyi Fei
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
hfq
sRNA
gene regulation
single-particle tracking
super-resolution imaging
Online Access:https://elifesciences.org/articles/64207

Internet

https://elifesciences.org/articles/64207

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