Desirability Function in analytical method development for determination of glitazones and metabolites employing HF-LPME

Abstract Thiazolidinedione, often shortened to TZD or glitazone, helps lower insulin resistance, which is the underlying problem for many people with type 2 diabetes. The two most known glitazones are pioglitazone (PGZ), with the brand name medicine Actos®, and rosiglitazone (RSG), which is Avandia®...

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Bibliographic Details
Main Authors: Matheus Santiago da Silva, Greyce Kelly Steinhorst Calixto, Débora Cristina de Oliveira, Felipe Rebello Lourenço, Leandro Augusto Calixto
Format: Article
Language:English
Published: Universidade de São Paulo 2022-05-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100568&lng=en&tlng=en