Sonic hedgehog and Wnt: antagonists in morphogenesis but collaborators in axon guidance

As indicated by their name, morphogens were first identified for their role in the formation of tissues early in development. Secreted from a source, they spread through the tissue to form gradients by which they affect the differentiation of precursor cells in a concentration-dependent manner. In t...

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Bibliographic Details
Main Authors: Evelyn Cecilia Avilés, Nicole Helen Wilson, Esther T. Stoeckli
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00086/full