Diversity of arterial cell and phenotypic heterogeneity induced by high-fat and high-cholesterol diet

Diversity of arterial cell and phenotypic heterogeneity induced by high-fat and high-cholesterol diet

Lipid metabolism disorder is the basis of atherosclerotic lesions, in which cholesterol and low-density lipoprotein (LDL) is the main factor involved with the atherosclerotic development. A high-fat and high-cholesterol diet can lead to this disorder in the human body, thus accelerating the process...

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Bibliographic Details
Main Authors: Jieqi Wen, Rongsong Ling, Ruiyue Chen, Siyan Zhang, Yarong Dai, Tingtao Zhang, Fanyu Guo, Qingxin Wang, Guixin Wang, Yizhou Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
single-cell RNA sequencing (scRNAseq)
western diet (WD)
cellular heterogeneity
endothelial dysfunction (ED)
atherosclerosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.971091/full

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https://www.frontiersin.org/articles/10.3389/fcell.2023.971091/full

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