Dysfunction of the Hippocampal-Lateral Septal Circuit Impairs Risk Assessment in Epileptic Mice

Dysfunction of the Hippocampal-Lateral Septal Circuit Impairs Risk Assessment in Epileptic Mice

Temporal lobe epilepsy, a chronic disease of the brain characterized by degeneration of the hippocampus, has impaired risk assessment. Risk assessment is vital for survival in complex environments with potential threats. However, the underlying mechanisms remain largely unknown. The intricate balanc...

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Bibliographic Details
Main Authors: Yi Cao, Chongyang Sun, Jianyu Huang, Peng Sun, Lulu Wang, Shuyu He, Jianxiang Liao, Zhonghua Lu, Yi Lu, Cheng Zhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
temporal lobe epilepsy
risk assessment
forthcoming approach
hippocampus
E/I imbalance
lateral septum
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.828891/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2022.828891/full

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