Scoring Targets of Transcription in Bacteria Rather than Focusing on Individual Binding Sites

Reliable identification of targets of bacterial regulators is necessary to understand bacterial gene expression regulation. These targets are commonly predicted by searching for high-scoring binding sites in the upstream genomic regions, which typically leads to a large number of false positives. In...

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Bibliographic Details
Main Authors: Marko Djordjevic, Magdalena Djordjevic, Evgeny Zdobnov
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02314/full