Protection and Safety Evaluation of Live Constructions Derived from the Pgm<sup>−</sup> and pPCP1<sup>−</sup> <i>Yersinia pestis</i> Strain
Based on a live attenuated <i>Yersinia pestis</i> KIM10(pCD1Ap) strain (Pgm<sup>−</sup>, pPCP1<sup>−</sup>), we attempted to engineer its lipid A species to achieve improvement of immunogenicity and safety. A mutant strain designated as YPS19(p...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-02-01
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Series: | Vaccines |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-393X/8/1/95 |