miR-124 Suppresses Pancreatic Ductal Adenocarcinoma Growth by Regulating Monocarboxylate Transporter 1-Mediated Cancer Lactate Metabolism

miR-124 Suppresses Pancreatic Ductal Adenocarcinoma Growth by Regulating Monocarboxylate Transporter 1-Mediated Cancer Lactate Metabolism

Background/Aims: Increasing evidence shows that reprogramming of energy metabolism is a hallmark of cancer. Considering the emergence of microRNAs as crucial modulators of cancer, this study aimed to better understand the molecular mechanisms of miR-124 in regulating glycolysis in human pancreatic c...

Full description

Bibliographic Details
Main Authors: De-Hai Wu, Hao Liang, Shou-Nan Lu, Hao Wang, Zhi-Lei Su, Lei Zhang, Jian-Qun Ma, Mian Guo, Sheng Tai, Shan Yu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
microRNA-124
Monocarboxylate transporter 1
Lactate metabolism
Pancreatic ductal adenocarcinoma
Online Access:https://www.karger.com/Article/FullText/494477

Internet

https://www.karger.com/Article/FullText/494477

Similar Items