CspA from <named-content content-type="genus-species">Borrelia burgdorferi</named-content> Inhibits the Terminal Complement Pathway

ABSTRACT In order to survive and persist in an immunocompetent human host, Borrelia burgdorferi controls the human immune attack and blocks the damaging effects of the activated complement system. These Gram-negative spirochetes use CspA (CRASP-1) and four additional immune evasion proteins to bind...

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Bibliographic Details
Main Authors: Teresia Hallström, Corinna Siegel, Matthias Mörgelin, Peter Kraiczy, Christine Skerka, Peter F. Zipfel
Format: Article
Language:English
Published: American Society for Microbiology 2013-08-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00481-13