NAD+ biosynthesis, aging, and disease [version 1; referees: 2 approved]

Nicotinamide adenine dinucleotide (NAD+) biosynthesis and its regulation have recently been attracting markedly increasing interest. Aging is marked by a systemic decrease in NAD+ across multiple tissues. The dysfunction of NAD+ biosynthesis plays a critical role in the pathophysiologies of multiple...

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Bibliographic Details
Main Authors: Sean Johnson, Shin–ichiro Imai
Format: Article
Language:English
Published: F1000 Research Ltd 2018-02-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/7-132/v1