The Co-N bond cleavage in the adenosyncobalamin cofactor in advance to glutamate mutase and methylmalonyl-CoA mutase processes

The Co-N bond cleavage in the adenosyncobalamin cofactor in advance to glutamate mutase and methylmalonyl-CoA mutase processes

The in vivo experiments show that the adenosylcobalamin cofactor in glutamate mutase and methylmalonyl-CoA mutase processes lose its dimethylbenzimidazole axial ligand before starting the enzymatic processes. Complete active space self-consistent field geometry optimization of the vitamin B12 active...

Bibliografske podrobnosti
Glavni avtor:	Tudor Spataru
Format:	Article
Jezik:	English
Izdano:	Academy of Sciences of Moldova, Institute of Chemistry 2023-12-01
Serija:	Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry
Teme:	dglutamate mutase methylmalonyl-coa mutase adenosylcobalamin cofactor vitamin b12 pseudo-jahn-teller effect
Online dostop:	http://cjm.ichem.md/the-co-n-bond-cleavage-in-the-adenosyncobalamin-cofactor-in-advance-to-glutamate-mutase-and-methylmalonyl-coa-mutase-processes

Podobne knjige/članki

A dodecylamine derivative of cyanocobalamin potently inhibits the activities of cobalamin-dependent methylmalonyl-CoA mutase and methionine synthase of Caenorhabditis elegans
od: Tomohiro Bito, et al.
Izdano: (2014-01-01)

Systematic literature review and meta-analysis on the epidemiology of methylmalonic acidemia (MMA) with a focus on MMA caused by methylmalonyl-CoA mutase (mut) deficiency
od: Tímea Almási, et al.
Izdano: (2019-04-01)

Biological Activity of Pseudovitamin B<sub>12</sub> on Cobalamin-Dependent Methylmalonyl-CoA Mutase and Methionine Synthase in Mammalian Cultured COS-7 Cells
od: Tomohiro Bito, et al.
Izdano: (2020-07-01)

Functional Analysis of A Novel Splicing Mutation in The Mutase Gene of Two Unrelated Pedigrees
od: Somayeh Ahmadloo, et al.
Izdano: (2016-09-01)

Structures of the human GTPase MMAA and vitamin B12-dependent methylmalonyl-CoA mutase and insight into their complex formation
od: Froese, D, et al.
Izdano: (2010)

Review: State of the knowledge on the importance of folates and cobalamin for dairy cow metabolism
od: C.L. Girard, et al.
Izdano: (2023-07-01)

Isolation and Expression of a cDNA Encoding Methylmalonic Aciduria Type A Protein from Euglena gracilis Z
od: Fumio Watanabe, et al.
Izdano: (2013-02-01)

Anesthetic management of a patient with methylmalonic acidemia: a case report
od: Yuta Uemura, et al.
Izdano: (2018-10-01)

The Design and Synthesis of N-Xanthone Benzenesulfonamides as Novel Phosphoglycerate Mutase 1 (PGAM1) Inhibitors
od: Penghui Wang, et al.
Izdano: (2018-06-01)

A chorismate mutase from Radopholus similis plays an essential role in pathogenicity
od: Sihua Yang, et al.
Izdano: (2024-03-01)

Different mutations in the MMUT gene are associated with the effect of vitamin B12 in a cohort of 266 Chinese patients with mut‐type methylmalonic acidemia: A retrospective study
od: Yue Yu, et al.
Izdano: (2021-11-01)

Decrease of disease‐related metabolites upon fasting in a hemizygous knock‐in mouse model (Mut‐ko/ki) of methylmalonic aciduria
od: Marie Lucienne, et al.
Izdano: (2021-03-01)

Development of Anthraquinone Analogues as Phosphoglycerate Mutase 1 Inhibitors
od: Ke Huang, et al.
Izdano: (2019-02-01)

Sumoylation-deficient phosphoglycerate mutase 2 impairs myogenic differentiation
od: Yi Zhang, et al.
Izdano: (2022-12-01)

Putative Bifunctional Chorismate Mutase/Prephenate Dehydratase Contributes to the Virulence of Acidovorax citrulli
od: Minyoung Kim, et al.
Izdano: (2020-09-01)

Persistent moderate methylmalonic aciduria in a patient with methylmalonyl CoA epimerase deficiency
od: Havva Yazıcı, et al.
Izdano: (2022-10-01)

Properties and Functional Analysis of Two Chorismate Mutases from Maritime Pine
od: Fernando de la Torre, et al.
Izdano: (2024-05-01)

Bisphosphoglycerate mutase predicts myocardial dysfunction and adverse outcome in sepsis: an observational cohort study
od: Long Huang, et al.
Izdano: (2024-02-01)

Phosphoglycerate mutase 1 knockdown inhibits prostate cancer cell growth, migration, and invasion
od: Yao-An Wen, et al.
Izdano: (2018-01-01)

Evolutionary Cycles for Pericyclic Reactions – Or Why We Keep Mutating Mutases
od: Kathrin Roderer, et al.
Izdano: (2009-06-01)

Biochemical Pattern of Methylmalonyl-CoA Epimerase Deficiency Identified in Newborn Screening: A Case Report
od: Evelina Maines, et al.
Izdano: (2024-07-01)

Identification of potential inhibitors for mycobacterial uridine diphosphogalactofuranose-galactopyranose mutase enzyme: A novel drug target through in silico approach
od: Tapaswini Nayak, et al.
Izdano: (2018-01-01)

Recombinant Toxoplasma gondii phosphoglycerate mutase 2 confers protective immunity against toxoplasmosis in BALB/c mice
od: Wang Hai-Long, et al.
Izdano: (2016-01-01)

<i>Trichoderma parareesei</i> Favors the Tolerance of Rapeseed (<i>Brassica napus</i> L.) to Salinity and Drought Due to a Chorismate Mutase
od: Jorge Poveda
Izdano: (2020-01-01)

Setting of graded levels of a protein in yeast by a t-degron technique as applied to phosphoglycerate mutase
od: Katja Heidrich, et al.
Izdano: (2002-07-01)

Multiomic analysis in fibroblasts of patients with inborn errors of cobalmin metabolism reveals concordance with clinical and metabolic variabilityResearch in context
od: Arnaud Wiedemann, et al.
Izdano: (2024-01-01)

The Miracle of Vitamin B12 Biochemistry
od: Tudor Spataru
Izdano: (2024-01-01)

Serum differential proteomic profiling of patients with isolated methylmalonic acidemia by iTRAQ
od: Sitao Li, et al.
Izdano: (2022-08-01)

Evaluating the Diagnostic Potential of Chorismate Mutase Poly-Clonal Peptide Antibody for the <i>Acanthamoeba</i> Keratitis in an Animal Model
od: Min-Jeong Kim, et al.
Izdano: (2023-03-01)

A putative 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase is involved in the virulence, carbohydrate metabolism, biofilm formation, twitching halo, and osmotic tolerance in Acidovorax citrulli
od: Jongchan Lee, et al.
Izdano: (2022-11-01)

Potential of Mycobacterium tuberculosis chorismate mutase (Rv1885c) as a novel TLR4-mediated adjuvant for dendritic cell-based cancer immunotherapy
od: Hyein Jeong, et al.
Izdano: (2022-12-01)

THE NATURE OF THE Co-C BOND CLEAVAGE PROCESSES IN METHYLCOB(II)ALAMIN AND ADENOSYLCOB(III)ALAMIN
od: Tudor Spataru, et al.
Izdano: (2016-06-01)

UDP-4-Keto-6-Deoxyglucose, a Transient Antifungal Metabolite, Weakens the Fungal Cell Wall Partly by Inhibition of UDP-Galactopyranose Mutase
od: Liang Ma, et al.
Izdano: (2017-12-01)

Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency
od: Alessandro Luciani, et al.
Izdano: (2020-02-01)

A secreted form of chorismate mutase (Rv1885c) in Mycobacterium bovis BCG contributes to pathogenesis by inhibiting mitochondria-mediated apoptotic cell death of macrophages
od: Mi-Hyun Lee, et al.
Izdano: (2023-12-01)

Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B12 delivery and repair
od: Romila Mascarenhas, et al.
Izdano: (2023-07-01)

Development of transgenic mice containing an introduced stop codon on the human methylmalonyl-CoA mutase locus.
od: Nicole E Buck, et al.
Izdano: (2012-01-01)

Biosynthesis of angelyl-CoA in Saccharomyces cerevisiae
od: Roberta Callari, et al.
Izdano: (2018-05-01)

Author Correction: Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency
od: Alessandro Luciani, et al.
Izdano: (2020-04-01)

Structures of the human GTPase MMAA and vitamin B12-dependent methylmalonyl-CoA mutase and insight into their complex formation.
od: Froese, D, et al.
Izdano: (2010)